Maleic Acid as a Co-Former for Pharmaceutically Active GABA Derivatives: Mechanochemistry or Solvent Crystallization?
In this study, we compare the mechanochemical and classical solvent crystallization methods for forming maleates of GABA and its pharmaceutically active derivatives: Pregabalin, Gabapentin, Phenibut, and Baclofen. Common characterization techniques, like powder and single crystal X-ray diffraction,...
Main Authors: | Daniel Komisarek, Ebru Taskiran, Vera Vasylyeva |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-03-01
|
Series: | Materials |
Subjects: | |
Online Access: | https://www.mdpi.com/1996-1944/16/6/2242 |
Similar Items
-
Main group mechanochemistry
by: Agota A. Gečiauskaitė, et al.
Published: (2017-10-01) -
Mechanochemistry: A Green Approach in the Preparation of Pharmaceutical Cocrystals
by: Mizraín Solares-Briones, et al.
Published: (2021-05-01) -
Synthesis of acylglycerol derivatives by mechanochemistry
by: Karen J. Ardila-Fierro, et al.
Published: (2019-03-01) -
Mechanochemistry, solvent-free and scale-up: Application toward coupling of acids and amines to amides
by: Liangdi Zhu, et al.
Published: (2023-01-01) -
Mechanochemistry assisted asymmetric organocatalysis: A sustainable approach
by: Pankaj Chauhan, et al.
Published: (2012-12-01)