pH of anti-VEGF agents in the human vitreous: low impact of very different formulations

Abstract Background The aim of the study was to measure pH changes of the human vitreous caused by the intravitreal drugs bevacizumab, ranibizumab, aflibercept, and ziv-aflibercept. Methods Fresh human vitreous samples were obtained during core vitrectomy (23-gauge) from patients with epiretinal gli...

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Bibliographic Details
Main Authors: Bianka Sobolewska, Peter Heiduschka, Karl-Ulrich Bartz-Schmidt, Focke Ziemssen
Format: Article
Language:English
Published: BMC 2017-06-01
Series:International Journal of Retina and Vitreous
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40942-017-0075-x