MOBILE pipeline enables identification of context-specific networks and regulatory mechanisms

Abstract Robust identification of context-specific network features that control cellular phenotypes remains a challenge. We here introduce MOBILE (Multi-Omics Binary Integration via Lasso Ensembles) to nominate molecular features associated with cellular phenotypes and pathways. First, we use MOBIL...

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Bibliographic Details
Main Authors: Cemal Erdem, Sean M. Gross, Laura M. Heiser, Marc R. Birtwistle
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-39729-2