Loss of Function <i>TGFBR2</i> Variant as a Contributing Factor in Generalized Pustular Psoriasis and Adult-Onset Immunodeficiency

Loss of Function <i>TGFBR2</i> Variant as a Contributing Factor in Generalized Pustular Psoriasis and Adult-Onset Immunodeficiency

Background: Generalized pustular psoriasis (GPP; MIM 614204) is a rare multisystemic autoinflammatory disease, characterized by episodes of acute generalized erythema and scaling developed with the spread of numerous sterile pustules. Adult-onset immunodeficiency syndrome (AOID) with anti-interferon...

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Bibliographic Details
Main Authors: Piranit Kantaputra, Teerada Daroontum, Mati Chuamanochan, Suteeraporn Chaowattanapanit, Worrachet Intachai, Bjorn Olsen, Thanapat Sastraruji, Sissades Tongsima, Chumpol Ngamphiw, Jatupol Kampuansai, Timothy C. Cox, Salin Kiratikanon
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Genes
Subjects:
adult-onset immunodeficiency syndrome
anti-interferon-γ autoantibody
TGFBR2 mutation
generalized pustular psoriasis
predisposing risk factor
pustular skin reaction
Online Access:https://www.mdpi.com/2073-4425/14/1/103

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https://www.mdpi.com/2073-4425/14/1/103

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