Efficacy of Recombinant Canine Distemper Virus Expressing Leishmania Antigen against Leishmania Challenge in Dogs.

Efficacy of Recombinant Canine Distemper Virus Expressing Leishmania Antigen against Leishmania Challenge in Dogs.

Canine distemper virus (CDV) vaccination confers long-term protection against CDV reinfection. To investigate the utility of CDV as a polyvalent vaccine vector for Leishmania, we generated recombinant CDVs, based on an avirulent Yanaka strain, that expressed Leishmania antigens: LACK, TSA, or LmSTI1...

Full description

Bibliographic Details
Main Authors: Ryuichi Miura, Takanori Kooriyama, Misako Yoneda, Akiko Takenaka, Miho Doki, Yasuyuki Goto, Chizu Sanjoba, Yasuyuki Endo, Tomoko Fujiyuki, Akihiro Sugai, Kyoko Tsukiyama-Kohara, Yoshitsugu Matsumoto, Hiroki Sato, Chieko Kai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4498809?pdf=render

Internet

http://europepmc.org/articles/PMC4498809?pdf=render

Similar Items