Role of a novel mouse mutant of the Galnt2tm1Lat/tm1Lat gene in otitis media

Role of a novel mouse mutant of the Galnt2tm1Lat/tm1Lat gene in otitis media

Genetic susceptibility is one of the most important causes of otitis media (OM). Mutant Galnt2 homozygote (Galnt2tm1Lat/tm1Lat) mimics human otitis media in comparable pathology and causes hearing loss. Otitis media is characterized by effusion and dysregulated mucosa proliferation and capillary exp...

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Bibliographic Details
Main Authors: Weijun Ma, Heng Li, Juan Hu, Ying Gao, Hui Lv, Xiaotong Zhang, Qing Zhang, Min Xu, Ying Cheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Neurology
Subjects:
genetic susceptibility
otitis media
mutant Galnt2 homozygote
hearing loss
mouse model
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2022.1054704/full

Internet

https://www.frontiersin.org/articles/10.3389/fneur.2022.1054704/full

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