The nuclear factor of activated T cells 5 (NFAT5) contributes to the renal corticomedullary differences in gene expression

Abstract The corticomedullary osmotic gradient between renal cortex and medulla induces a specific spatial gene expression pattern. The factors that controls these differences are not fully addressed. Adaptation to hypertonic environment is mediated by the actions of the nuclear factor of activated...

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Bibliographic Details
Main Authors: Dmitry Chernyakov, Annika Fischer, Max Brandau, Federica Petrillo, Robert A. Fenton, Bayram Edemir
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-24237-y