Peptide-Mucin Binding and Biosimilar Mucus-Permeating Properties

Peptide-Mucin Binding and Biosimilar Mucus-Permeating Properties

This study aimed to understand the role of the mucus layer (a biological hydrogel) in the transport mechanisms of peptides. Using established in vitro models, the mucin-binding activity and mucus-permeating property of peptides were determined. Uncharged peptides with relatively high hydrophilicity,...

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Bibliographic Details
Main Authors: Xiaohong Sun, Raliat O. Abioye, Ogadimma D. Okagu, Chibuike C. Udenigwe
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Gels
Subjects:
mucin-binding activity
biosimilar mucus-permeating property
in vitro model
mucin binding-mucus permeability relation
hydrophobicity index
bioavailability
Online Access:https://www.mdpi.com/2310-2861/8/1/1

Internet

https://www.mdpi.com/2310-2861/8/1/1

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