Hypolipidemic and insulin sensitizing effects of salsalate beyond suppressing inflammation in a prediabetic rat model

Hypolipidemic and insulin sensitizing effects of salsalate beyond suppressing inflammation in a prediabetic rat model

Background and aims: Low-grade chronic inflammation plays an important role in the pathogenesis of metabolic syndrome, type 2 diabetes and their complications. In this study, we investigated the effects of salsalate, a non-steroidal anti-inflammatory drug, on metabolic disturbances in an animal mode...

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Bibliographic Details
Main Authors:	Martina Hüttl, Irena Markova, Denisa Miklánková, Iveta Zapletalova, Petr Kujal, Jan Šilhavý, Michal Pravenec, Hana Malinska
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-04-01
Series:	Frontiers in Pharmacology
Subjects:	salsalate low-grade inflammation prediabetes lipid metabolism cytochrome P450 oxidative stress
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2023.1117683/full

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