METTL17 coordinates ferroptosis and tumorigenesis by regulating mitochondrial translation in colorectal cancer

METTL17 coordinates ferroptosis and tumorigenesis by regulating mitochondrial translation in colorectal cancer

Ferroptosis, an iron-dependent lipid peroxidation-induced form of regulated cell death, shows great promise as a cancer therapy strategy. Despite the critical role of mitochondria in ferroptosis regulation, the underlying mechanisms remain elusive. This study reveals that the mitochondrial protein M...

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Bibliographic Details
Main Authors: Hao Li, Kailun Yu, Huilong Hu, Xiandan Zhang, Siyu Zeng, Jiawen Li, Xiaoning Dong, Xusheng Deng, Jianhui Zhang, Yongyou Zhang
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:Redox Biology
Subjects:
METTL17
Ferroptosis
Mitochondrial RNA methylation
Colorectal cancer (CRC)
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231724000636

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http://www.sciencedirect.com/science/article/pii/S2213231724000636

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