Diversity of KIR genes and their HLA-C ligands in Ugandan populations with historically varied malaria transmission intensity

Diversity of KIR genes and their HLA-C ligands in Ugandan populations with historically varied malaria transmission intensity

Abstract Background Malaria is one of the most serious infectious diseases in the world. The malaria burden is greatly affected by human immunity, and immune responses vary between populations. Genetic diversity in KIR and HLA-C genes, which are important in immunity to infectious diseases, is likel...

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Bibliographic Details
Main Authors: Stephen Tukwasibwe, James A. Traherne, Olympe Chazara, Jyothi Jayaraman, John Trowsdale, Ashley Moffett, Wei Jiang, Joaniter I. Nankabirwa, John Rek, Emmanuel Arinaitwe, Samuel L. Nsobya, Maxine Atuheirwe, Mubiru Frank, Anguzu Godwin, Prasanna Jagannathan, Stephen Cose, Moses R. Kamya, Grant Dorsey, Philip J. Rosenthal, Francesco Colucci, Annettee Nakimuli
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Malaria Journal
Subjects:
Genetic diversity
Human leukocyte antigen
Killer-cell immunoglobulin-like receptor
Malaria
Uganda
Online Access:https://doi.org/10.1186/s12936-021-03652-y

Internet

https://doi.org/10.1186/s12936-021-03652-y

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