tappAS: a comprehensive computational framework for the analysis of the functional impact of differential splicing
Abstract Recent advances in long-read sequencing solve inaccuracies in alternative transcript identification of full-length transcripts in short-read RNA-Seq data, which encourages the development of methods for isoform-centered functional analysis. Here, we present tappAS, the first framework to en...
Main Authors: | , , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-05-01
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Series: | Genome Biology |
Online Access: | http://link.springer.com/article/10.1186/s13059-020-02028-w |