Host Genetic Variation Impacts SARS-CoV-2 Vaccination Response in the Diversity Outbred Mouse Population

Host Genetic Variation Impacts SARS-CoV-2 Vaccination Response in the Diversity Outbred Mouse Population

The COVID-19 pandemic led to the rapid and worldwide development of highly effective vaccines against SARS-CoV-2. However, there is significant individual-to-individual variation in vaccine efficacy due to factors including viral variants, host age, immune status, environmental and host genetic fact...

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Bibliographic Details
Main Authors: Marta C. Cruz Cisneros, Elizabeth J. Anderson, Brea K. Hampton, Breantié Parotti, Sanjay Sarkar, Sharon Taft-Benz, Timothy A. Bell, Matthew Blanchard, Jacob A. Dillard, Kenneth H. Dinnon, Pablo Hock, Sarah R. Leist, Emily A. Madden, Ginger D. Shaw, Ande West, Ralph S. Baric, Victoria K. Baxter, Fernando Pardo-Manuel de Villena, Mark T. Heise, Martin T. Ferris
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Vaccines
Subjects:
Diversity Outbred
host genetic diversity
SARS-CoV-2
vaccination
Online Access:https://www.mdpi.com/2076-393X/12/1/103

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https://www.mdpi.com/2076-393X/12/1/103

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