Clamp loader ATPases and the evolution of DNA replication machinery
<p>Abstract</p> <p>Clamp loaders are pentameric ATPases of the AAA+ family that operate to ensure processive DNA replication. They do so by loading onto DNA the ring-shaped sliding clamps that tether the polymerase to the DNA. Structural and biochemical analysis of clamp loaders ha...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2012-04-01
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| Series: | BMC Biology |
| Online Access: | http://www.biomedcentral.com/1741-7007/10/34 |