Germline Pathogenic Variant Prevalence Among Latin American and US Hispanic Individuals Undergoing Testing for Hereditary Breast and Ovarian Cancer: A Cross-Sectional Study

PURPOSETo report on pathogenic germline variants detected among individuals undergoing genetic testing for hereditary breast and/or ovarian cancer (HBOC) from Latin America and compare them with self-reported Hispanic individuals from the United States.METHODSIn this cross-sectional study, unrelated...

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Bibliographic Details
Main Authors: Carlos Andrés Ossa Gomez, Maria Isabel Achatz, Mabel Hurtado, María Carolina Sanabria-Salas, Yasser Sullcahuaman, Yanin Chávarri-Guerra, Julie Dutil, Sarah M. Nielsen, Edward D. Esplin, Scott T. Michalski, Sara L. Bristow, Kathryn E. Hatchell, Robert L. Nussbaum, Daniel E. Pineda-Alvarez, Patricia Ashton-Prolla
Format: Article
Language:English
Published: American Society of Clinical Oncology 2022-07-01
Series:JCO Global Oncology
Online Access:https://ascopubs.org/doi/10.1200/GO.22.00104