Association between Breast Cancer Polygenic Risk Score and Chemotherapy-Induced Febrile Neutropenia: Null Results

Association between Breast Cancer Polygenic Risk Score and Chemotherapy-Induced Febrile Neutropenia: Null Results

Background: The hypothesis that breast cancer (BC) susceptibility variants are linked to chemotherapy-induced toxicity has been previously explored. Here, we investigated the association between a validated 313-marker-based BC polygenic risk score (PRS) and chemotherapy-induced neutropenia without f...

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Bibliographic Details
Main Authors: Seeu Si Ong, Peh Joo Ho, Alexis Jiaying Khng, Elaine Hsuen Lim, Fuh Yong Wong, Benita Kiat-Tee Tan, Swee Ho Lim, Ern Yu Tan, Su-Ming Tan, Veronique Kiak Mien Tan, Rebecca Dent, Tira Jing Ying Tan, Joanne Ngeow, Preetha Madhukumar, Julie Liana Bte Hamzah, Yirong Sim, Geok Hoon Lim, Jinnie Siyan Pang, Veronica Siton Alcantara, Patrick Mun Yew Chan, Juliana Jia Chuan Chen, Sherwin Kuah, Jaime Chin Mui Seah, Shaik Ahmad Buhari, Siau Wei Tang, Celene Wei Qi Ng, Jingmei Li, Mikael Hartman
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Cancers
Subjects:
febrile neutropenia
neutropenic fever
breast cancer
polygenic risk score
PRS
Online Access:https://www.mdpi.com/2072-6694/14/11/2714

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https://www.mdpi.com/2072-6694/14/11/2714

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