Longitudinal Cytokine Profiling Identifies GRO-α and EGF as Potential Biomarkers of Disease Progression in Essential Thrombocythemia

Abstract. Myeloproliferative neoplasms (MPNs) are characterized by deregulation of mature blood cell production and increased risk of myelofibrosis (MF) and leukemic transformation. Numerous driver mutations have been identified but substantial disease heterogeneity remains unexplained, implying the...

Full description

Bibliographic Details
Main Authors: Nina F. Øbro, Jacob Grinfeld, Miriam Belmonte, Melissa Irvine, Mairi S. Shepherd, Tata Nageswara Rao, Axel Karow, Lisa M. Riedel, Oliva B. Harris, E. Joanna Baxter, Jyoti Nangalia, Anna Godfrey, Claire N. Harrison, Juan Li, Radek C. Skoda, Peter J. Campbell, Anthony R. Green, David G. Kent
Format: Article
Language:English
Published: Wiley 2020-06-01
Series:HemaSphere
Online Access:http://journals.lww.com/10.1097/HS9.0000000000000371