Overexpression of Mdm2 induces crizotinib resistance in targeted therapy for ALK-positive NSCLC
Objective To investigate the effect of overexpression of murine double minute 2 (Mdm2) on the sensitivity to crizotinib in the anaplastic lymphoma kinase (ALK)-positive non-small cell lung cancer (NSCLC) cell line H3122. Methods H3122 cells with Mdm2 overexpression were established by transfection o...
| Main Authors: | , , |
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| Format: | Article |
| Language: | zho |
| Published: |
Editorial Office of Journal of Army Medical University
2022-12-01
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| Series: | 陆军军医大学学报 |
| Subjects: | |
| Online Access: | http://aammt.tmmu.edu.cn/Upload/rhtml/202209006.htm |