Optimal designs for population pharmacokinetic studies of the partner drugs co-administered with artemisinin derivatives in patients with uncomplicated falciparum malaria

<p>Abstract</p> <p>Background</p> <p>Artemisinin-based combination therapy (ACT) is currently recommended as first-line treatment for uncomplicated malaria, but of concern, it has been observed that the effectiveness of the main artemisinin derivative, artesunate, has b...

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Bibliographic Details
Main Authors: Jamsen Kris M, Duffull Stephen B, Tarning Joel, Lindegardh Niklas, White Nicholas J, Simpson Julie A
Format: Article
Language:English
Published: BMC 2012-07-01
Series:Malaria Journal
Subjects:
Online Access:http://www.malariajournal.com/content/11/1/143