A slow-cycling/quiescent cells subpopulation is involved in glioma invasiveness
Abstract Pediatric and adult high-grade gliomas are the most common primary malignant brain tumors, with poor prognosis due to recurrence and tumor infiltration after therapy. Quiescent cells have been implicated in tumor recurrence and treatment resistance, but their direct visualization and target...
Main Authors: | , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-08-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-022-32448-0 |