Activated DRP1 promotes mitochondrial fission and induces glycolysis in ATII cells under hyperoxia

Activated DRP1 promotes mitochondrial fission and induces glycolysis in ATII cells under hyperoxia

Abstract Backgroud Recent studies have reported mitochondrial damage and metabolic dysregulation in BPD, but the changes in mitochondrial dynamics and glucose metabolic reprogramming in ATII cells and their regulatory relationship have not been reported. Methods Neonatal rats in this study were divi...

תיאור מלא

מידע ביבליוגרפי
Main Authors: Tong Sun, Haiyang Yu, Dingning Zhang, Danni Li, Jianhua Fu
פורמט: Article
שפה:English
יצא לאור: BMC 2024-12-01
סדרה:Respiratory Research
נושאים:
Mitochondrial fission
Metabolic reprogramming
Bronchopulmonary dysplasia
ATII cells
DRP1 signaling pathway
גישה מקוונת:https://doi.org/10.1186/s12931-024-03083-8

אינטרנט

https://doi.org/10.1186/s12931-024-03083-8

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