Activated DRP1 promotes mitochondrial fission and induces glycolysis in ATII cells under hyperoxia

Activated DRP1 promotes mitochondrial fission and induces glycolysis in ATII cells under hyperoxia

Abstract Backgroud Recent studies have reported mitochondrial damage and metabolic dysregulation in BPD, but the changes in mitochondrial dynamics and glucose metabolic reprogramming in ATII cells and their regulatory relationship have not been reported. Methods Neonatal rats in this study were divi...

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Dettagli Bibliografici
Autori principali:	Tong Sun, Haiyang Yu, Dingning Zhang, Danni Li, Jianhua Fu
Natura:	Articolo
Lingua:	English
Pubblicazione:	BMC 2024-12-01
Serie:	Respiratory Research
Soggetti:	Mitochondrial fission Metabolic reprogramming Bronchopulmonary dysplasia ATII cells DRP1 signaling pathway
Accesso online:	https://doi.org/10.1186/s12931-024-03083-8

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