Activated DRP1 promotes mitochondrial fission and induces glycolysis in ATII cells under hyperoxia

Activated DRP1 promotes mitochondrial fission and induces glycolysis in ATII cells under hyperoxia

Abstract Backgroud Recent studies have reported mitochondrial damage and metabolic dysregulation in BPD, but the changes in mitochondrial dynamics and glucose metabolic reprogramming in ATII cells and their regulatory relationship have not been reported. Methods Neonatal rats in this study were divi...

Полное описание

Библиографические подробности
Главные авторы:	Tong Sun, Haiyang Yu, Dingning Zhang, Danni Li, Jianhua Fu
Формат:	Статья
Язык:	English
Опубликовано:	BMC 2024-12-01
Серии:	Respiratory Research
Предметы:	Mitochondrial fission Metabolic reprogramming Bronchopulmonary dysplasia ATII cells DRP1 signaling pathway
Online-ссылка:	https://doi.org/10.1186/s12931-024-03083-8

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