RET splice site variants in medullary thyroid carcinoma

RET splice site variants in medullary thyroid carcinoma

Introduction: Medullary thyroid carcinoma (MTC) is an aggressive cancer that is often caused by driver mutations in RET. Splice site variants (SSV) reflect changes in mRNA processing, which may alter protein function. RET SSVs have been described in thyroid tumors in general but have not been extens...

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Bibliographic Details
Main Authors: Daryoush Saeed-Vafa, Kyriakos Chatzopoulos, Juan Hernandez-Prera, Pedro Cano, James J. Saller, Julie E. Hallanger Johnson, Bryan McIver, Theresa A. Boyle
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Genetics
Subjects:
medullary thyroid carcinoma
RET
splice site variant
thyroid
endocrine
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2024.1377158/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2024.1377158/full

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