Epidermal growth factor receptor (EGFR) mutations in lung cancer: preclinical and clinical data

Epidermal growth factor receptor (EGFR) mutations in lung cancer: preclinical and clinical data

Lung cancer leads cancer-related mortality worldwide. Non-small-cell lung cancer (NSCLC), the most prevalent subtype of this recalcitrant cancer, is usually diagnosed at advanced stages, and available systemic therapies are mostly palliative. The probing of the NSCLC kinome has identified numerous n...

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Bibliographic Details
Main Authors: S.E.D.C. Jorge, S.S. Kobayashi, D.B. Costa
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2014-11-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Mutation
Lung cancer
Non-small-cell lung cancer
EGFR
EGFR inhibitor
Precision therapies
Resistance
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2014001100929&lng=en&tlng=en

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2014001100929&lng=en&tlng=en

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