Transcriptomic signature of Bexarotene (Rexinoid LGD1069) on mammary gland from three transgenic mouse mammary cancer models

<p>Abstract</p> <p>Background</p> <p>The rexinoid bexarotene (LGD1069, Targretin) is a highly selective retinoid × receptor (RXR) agonist that inhibits the growth of pre-malignant and malignant breast cells. Bexarotene was shown to suppress the development of breast can...

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Bibliographic Details
Main Authors: Bissonnette Reid P, Hill Jamal, Zhang Yun, Kittrell Frances S, Gaddis Sally, Levy Carla C, Hu Yuhui, Abba Martin C, Medina Daniel, Brown Powel H, Aldaz C
Format: Article
Language:English
Published: BMC 2008-09-01
Series:BMC Medical Genomics
Online Access:http://www.biomedcentral.com/1755-8794/1/40