Evidence-based nanoscopic and molecular framework for excipient functionality in compressed orally disintegrating tablets.

Evidence-based nanoscopic and molecular framework for excipient functionality in compressed orally disintegrating tablets.

The work investigates the adhesive/cohesive molecular and physical interactions together with nanoscopic features of commonly used orally disintegrating tablet (ODT) excipients microcrystalline cellulose (MCC) and D-mannitol. This helps to elucidate the underlying physico-chemical and mechanical mec...

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Bibliographic Details
Main Authors: Ali Al-Khattawi, Hamad Alyami, Bill Townsend, Xianghong Ma, Afzal R Mohammed
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25025427/pdf/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25025427/pdf/?tool=EBI

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