Pulse Drug Delivery Strategy Based on Pharmacokinetic-Pharmacodynamic (PK-PD) Model of Tolerance

In clinical practice, the curative effect of drugs will decrease due to the increase of drug resistance, especially in stable long-term drug delivery systems. Intermittent drug dosing is an effective method to reduce drug resistance and achieve a better effect comparing with consistent one. The rela...

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Bibliographic Details
Main Authors: Jiali Ai, Jindong Dai, Chi Zhai, Wei Sun
Format: Article
Language:English
Published: AIDIC Servizi S.r.l. 2022-09-01
Series:Chemical Engineering Transactions
Online Access:https://www.cetjournal.it/index.php/cet/article/view/12770