Consistency of tumor and immune cell programmed cell death ligand-1 expression within and between tumor blocks using the VENTANA SP263 assay

Consistency of tumor and immune cell programmed cell death ligand-1 expression within and between tumor blocks using the VENTANA SP263 assay

Abstract Background Several anti-programmed cell death-1 (PD-1) and anti-programmed cell death ligand-1 (PD-L1) therapies have shown encouraging safety and clinical activity in a variety of tumor types. A potential role for PD-L1 testing in identifying patients that are more likely to respond to tre...

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Bibliographic Details
Main Authors: Paul Scorer, Marietta Scott, Nicola Lawson, Marianne J. Ratcliffe, Craig Barker, Marlon C. Rebelatto, Jill Walker
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Diagnostic Pathology
Subjects:
PD-L1
Heterogeneity
Assay
Concordance
Consistency
Reproducibility
Online Access:http://link.springer.com/article/10.1186/s13000-018-0725-9

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http://link.springer.com/article/10.1186/s13000-018-0725-9

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