Cryopreservation does not change the performance and characteristics of allogenic mesenchymal stem cells highly over-expressing a cytoplasmic therapeutic transgene for cancer treatment

Abstract Background Mesenchymal stem cells (MSCs) driven gene directed enzyme prodrug therapy is a promising approach to deliver therapeutic agents to target heterogenous solid tumours. To democratize such a therapy, cryopreservation along with cold chain transportation is an essential part of the l...

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Bibliographic Details
Main Authors: Yoon Khei Ho, Kin Man Loke, Jun Yung Woo, Yee Lin Lee, Heng-Phon Too
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:https://doi.org/10.1186/s13287-022-03198-z