Unraveling molecular characteristic of fluoride neurotoxicity on U87 glial-like cells: insights from transcriptomic and proteomic approach

Unraveling molecular characteristic of fluoride neurotoxicity on U87 glial-like cells: insights from transcriptomic and proteomic approach

The potential of fluoride (F) as a neurotoxicant in humans is still controversial in the literature. However, recent studies have raised the debate by showing different mechanism of F-induced neurotoxicity, as oxidative stress, energy metabolism and inflammation in the central nervous system (CNS)....

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Bibliographic Details
Main Authors: Bruna Puty, Leonardo Oliveira Bittencourt, Leidiane Alencar Oliveira Lima, Jéssica Rodrigues Plaça, Aline Dionizio, Marília Afonso Rabelo Buzalaf, Bruno Duarte Gomes, Edivaldo Herculano Correa de Oliveira, Rafael Rodrigues Lima
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Cellular Neuroscience
Subjects:
neurotoxicity
fluoride
proteomic
transcriptomic
glia
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2023.1153198/full

Internet

https://www.frontiersin.org/articles/10.3389/fncel.2023.1153198/full

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