2,4-Dinitrophenol as an Uncoupler Augments the Anthracyclines Toxicity against Prostate Cancer Cells

2,4-Dinitrophenol as an Uncoupler Augments the Anthracyclines Toxicity against Prostate Cancer Cells

One of the strategies for the treatment of advanced cancer diseases is targeting the energy metabolism of the cancer cells. The compound 2,4-DNP (2,4-dinitrophenol) disrupts the cell energy metabolism through the ability to decouple oxidative phosphorylation. The aim of the study was to determine th...

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Bibliographic Details
Main Authors: Grzegorz Adamczuk, Ewelina Humeniuk, Kamila Adamczuk, Aneta Grabarska, Jarosław Dudka
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Molecules
Subjects:
uncoupler
2,4-dinitrophenol
anthracyclines
doxorubicin
epirubicin
prostate cancer
Online Access:https://www.mdpi.com/1420-3049/27/21/7227

Internet

https://www.mdpi.com/1420-3049/27/21/7227

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