Multi-Targeting Intranasal Nanoformulation as a Therapeutic for Alzheimer’s Disease

Multi-Targeting Intranasal Nanoformulation as a Therapeutic for Alzheimer’s Disease

Melatonin, insulin, and Δ9-tetrahydrocannabinol (THC) have been shown to reverse cognitive deficits and attenuate neuropathologies in transgenic mouse models of Alzheimer’s disease (AD) when used individually. Here, we evaluated the therapeutic properties of long-term intranasal treatment with a nov...

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Bibliographic Details
Main Authors: Oksana Fihurka, Yanhong Wang, Yuzhu Hong, Xiaoyang Lin, Ning Shen, Haiqiang Yang, Breanna Brown, Marcus Mommer, Tarek Zieneldien, Yitong Li, Janice Kim, Minghua Li, Jianfeng Cai, Qingyu Zhou, Chuanhai Cao
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Biomolecules
Subjects:
melatonin
insulin
THC
intranasal treatment
APP/PS1 mice
Alzheimer’s disease
Online Access:https://www.mdpi.com/2218-273X/13/2/232

Internet

https://www.mdpi.com/2218-273X/13/2/232

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