Synthesis and biological evaluation of fluorine substituted pyrazolo[4,3-e][1,2,4]triazines as purine analogues

Some more new fluorine substituted pyrazolo[4,3-e][1,2,4]triazine derivatives (2–5), 7, 10, 14, 17 have been synthesized derived from hydrazinolysis of N-acyl/aroyl/dithioic formamido-2,3-dimethyl-1-phenyl-pyrazolo-5-ones which are obtained from 4-aminoantipyrine 1. The enzymatic assays (cellobaise...

Full description

Bibliographic Details
Main Authors: Reda M. Abdel-Rahman, Rihab F. Angawi, Aisha R. Al-Mehmadi
Format: Article
Language:English
Published: Elsevier 2017-05-01
Series:Journal of Saudi Chemical Society
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1319610316301089