PROM2 overexpression induces metastatic potential through epithelial‐to‐mesenchymal transition and ferroptosis resistance in human cancers

PROM2 overexpression induces metastatic potential through epithelial‐to‐mesenchymal transition and ferroptosis resistance in human cancers

Abstract Introduction Despite considerable therapeutic advances in the last 20 years, metastatic cancers remain a major cause of death. We previously identified prominin‐2 (PROM2) as a biomarker predictive of distant metastases and decreased survival, thus providing a promising bio‐target. In this t...

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Bibliographic Details
Main Authors: Justine Paris, Claire Wilhelm, Celeste Lebbé, Mohammed Elmallah, Frédéric Pamoukdjian, Audrey Héraud, Guillaume Gapihan, Aurore Van De Walle, Van Nhan Tran, Diaddin Hamdan, Clara Allayous, Maxime Battistella, Emmanuel Van Glabeke, Kah Wai Lim, Christophe Leboeuf, Sébastien Roger, Géraldine Falgarone, Anh Tuan Phan, Guilhem Bousquet
Format: Article
Language:English
Published: Wiley 2024-03-01
Series:Clinical and Translational Medicine
Subjects:
breast cancer
epithelial‐to‐mesenchymal transition
ferroptosis resistance
melanoma
metastases
prominin‐2
Online Access:https://doi.org/10.1002/ctm2.1632

Internet

https://doi.org/10.1002/ctm2.1632

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