Modulation of the immune system by the gut microbiota in the development of type 1 diabetes

Modulation of the immune system by the gut microbiota in the development of type 1 diabetes

T1D is an autoimmune disease characterized by T cell-mediated destruction of insulin-producing β-cells in the pancreatic islets of Langerhans, resulting in hyperglycemia, with patients requiring lifelong insulin treatment. Many studies have shown that genetics alone are not sufficient for the increa...

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Bibliographic Details
Main Authors: James A. Pearson, Andrew Agriantonis, F. Susan Wong, Li Wen
Format: Article
Language:English
Published: Taylor & Francis Group 2018-11-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
gut microbiota
type 1 diabetes
nod mice
therapy
Online Access:http://dx.doi.org/10.1080/21645515.2018.1514354

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