Generation of one iPSC line (IMEDEAi006-A) from an early-onset familial Alzheimer's Disease (fAD) patient carrying the E280A mutation in the PSEN1 gene

Generation of one iPSC line (IMEDEAi006-A) from an early-onset familial Alzheimer's Disease (fAD) patient carrying the E280A mutation in the PSEN1 gene

The mutation E280A in PSEN1 (presenilin-1) is the most common cause of early-onset familial Alzheimer's Disease (fAD). It presents autosomal dominant inheritance and frequently leads to the manifestation of the disease in relatively young individuals. Here we report the generation of one PSEN1...

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Bibliographic Details
Main Authors: Sara Vallejo-Diez, Aarne Fleischer, Jose María Martín-Fernández, Almudena Sánchez-Gilabert, Mónica Castresana, David Aguillón, Andrés Villegas, Claudio A. Mastronardi, Lady G. Espinosa, Mauricio Arcos-Burgos, Ángel del Pozo, Enara Herrán, Eusebio Gainza, Mario Isaza-Ruget, Francisco Lopera, Daniel Bachiller
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506119300704

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http://www.sciencedirect.com/science/article/pii/S1873506119300704

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