Minimal Crossover between Mutations Associated with Omicron Variant of SARS-CoV-2 and CD8+ T-Cell Epitopes Identified in COVID-19 Convalescent Individuals

Minimal Crossover between Mutations Associated with Omicron Variant of SARS-CoV-2 and CD8+ T-Cell Epitopes Identified in COVID-19 Convalescent Individuals

ABSTRACT There is a growing concern that ongoing evolution of SARS-CoV-2 could lead to variants of concern (VOC) that are capable of avoiding some or all of the multifaceted immune response generated by both prior infection or vaccination, with the recently described B.1.1.529 (Omicron) VOC being of...

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Bibliographic Details
Main Authors: Andrew D. Redd, Alessandra Nardin, Hassen Kared, Evan M. Bloch, Brian Abel, Andrew Pekosz, Oliver Laeyendecker, Michael Fehlings, Thomas C. Quinn, Aaron A. R. Tobian
Format: Article
Language:English
Published: American Society for Microbiology 2022-04-01
Series:mBio
Subjects:
convalescent patients
Omicron
CD8+ T cell
COVID-19
convalescent plasma
SARS-CoV-2
Online Access:https://journals.asm.org/doi/10.1128/mbio.03617-21

Internet

https://journals.asm.org/doi/10.1128/mbio.03617-21

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