Mutational Landscape of the Proglucagon-Derived Peptides

Strong efforts have been placed on understanding the physiological roles and therapeutic potential of the proglucagon peptide hormones including glucagon, GLP-1 and GLP-2. However, little is known about the extent and magnitude of variability in the amino acid composition of the proglucagon precurso...

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Bibliographic Details
Main Authors: Peter Lindquist, Jakob S. Madsen, Hans Bräuner-Osborne, Mette M. Rosenkilde, Alexander S. Hauser
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.698511/full