Rare Germline Genetic Variants and the Risks of Epithelial Ovarian Cancer
A family history of ovarian or breast cancer is the strongest risk factor for epithelial ovarian cancer (EOC). Germline deleterious variants in the <i>BRCA1</i> and <i>BRCA2</i> genes confer EOC risks by age 80, of 44% and 17% respectively. The mismatch repair genes, particul...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-10-01
|
| Series: | Cancers |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2072-6694/12/10/3046 |