Topological relationships between perivascular spaces and progression of white matter hyperintensities: A pilot study in a sample of the Lothian Birth Cohort 1936

Enlarged perivascular spaces (PVS) and white matter hyperintensities (WMH) are features of cerebral small vessel disease which can be seen in brain magnetic resonance imaging (MRI). Given the associations and proposed mechanistic link between PVS and WMH, they are hypothesized to also have topologic...

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Bibliographic Details
Main Authors: Abbie Barnes, Lucia Ballerini, Maria del C. Valdés Hernández, Francesca M. Chappell, Susana Muñoz Maniega, Rozanna Meijboom, Ellen V. Backhouse, Michael S. Stringer, Roberto Duarte Coello, Rosalind Brown, Mark E. Bastin, Simon R. Cox, Ian J. Deary, Joanna M. Wardlaw
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Neurology
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Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2022.889884/full