Human adipose-derived mesenchymal stem cells seeded into a collagen-hydroxyapatite scaffold promote bone augmentation after implantation in the mouse

Abstract Traumatic injury or surgical excision of diseased bone tissue usually require the reconstruction of large bone defects unable to heal spontaneously, especially in older individuals. This is a big challenge requiring the development of biomaterials mimicking the bone structure and capable of...

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Bibliographic Details
Main Authors: Giovanna Calabrese, Raffaella Giuffrida, Stefano Forte, Claudia Fabbi, Elisa Figallo, Lucia Salvatorelli, Lorenzo Memeo, Rosalba Parenti, Massimo Gulisano, Rosario Gulino
Format: Article
Language:English
Published: Nature Portfolio 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-07672-0