Keap1-targeting microRNA-941 protects endometrial cells from oxygen and glucose deprivation-re-oxygenation via activation of Nrf2 signaling

Keap1-targeting microRNA-941 protects endometrial cells from oxygen and glucose deprivation-re-oxygenation via activation of Nrf2 signaling

Abstract Background Mimicking ischemia-reperfusion injury, oxygen and glucose deprivation (OGD)-re-oxygenation (OGDR) applied to endometrial cells produces significant oxidative stress and programmed necrosis, which can be inhibited by nuclear-factor-E2-related factor 2 (Nrf2) signaling. MicroRNA (m...

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Bibliographic Details
Main Authors: Shu-ping Li, Wei-nan Cheng, Ya Li, Hong-bin Xu, Hui Han, Ping Li, Deng-Xia Zhang
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Cell Communication and Signaling
Subjects:
microRNA-941
Nrf2
Keap1
Endometrial cells
Ischemia-reperfusion injury
Online Access:http://link.springer.com/article/10.1186/s12964-020-0526-0

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http://link.springer.com/article/10.1186/s12964-020-0526-0

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