Gut Dysbiosis and Its Associations with Gut Microbiota-Derived Metabolites in Dogs with Myxomatous Mitral Valve Disease

Gut Dysbiosis and Its Associations with Gut Microbiota-Derived Metabolites in Dogs with Myxomatous Mitral Valve Disease

ABSTRACT Gut dysbiosis and gut microbiota-derived metabolites, including bile acid (BA), short-chain fatty acid, and trimethylamine N-oxide (TMAO), are associated with cardiovascular disease. Canine myxomatous mitral valve disease (MMVD) is a model for human MMVD. The aim of the study is to evaluate...

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Bibliographic Details
Main Authors: Qinghong Li, Éva Larouche-Lebel, Kerry A. Loughran, Terry P. Huh, Jan S. Suchodolski, Mark A. Oyama
Format: Article
Language:English
Published: American Society for Microbiology 2021-04-01
Series:mSystems
Subjects:
microbiota
trimethylamine N-oxide
mitral valve disease
canine
dysbiosis
bile acid
Online Access:https://journals.asm.org/doi/10.1128/mSystems.00111-21

Internet

https://journals.asm.org/doi/10.1128/mSystems.00111-21

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