Effects of P<sub>4</sub> Antagonist RU486 on VEGF and Its Receptors’ Signaling during the In Vivo Transition from the Preovulatory to Periovulatory Phase of Ovarian Follicles

Effects of P<sub>4</sub> Antagonist RU486 on VEGF and Its Receptors’ Signaling during the In Vivo Transition from the Preovulatory to Periovulatory Phase of Ovarian Follicles

The development of an adequate blood vessel network is crucial for the accomplishment of ovarian follicle growth and ovulation, which is necessary to support the proliferative and endocrine functions of the follicular cells. Although the Vascular Endothelial Growth Factor (VEGF) through gonadotropin...

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Bibliographic Details
Main Authors: Annunziata Mauro, Paolo Berardinelli, Valentina Russo, Nicola Bernabò, Alessandra Martelli, Delia Nardinocchi, Oriana Di Giacinto, Maura Turriani, Barbara Barboni
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:International Journal of Molecular Sciences
Subjects:
gonadotropins
progesterone
signal transduction
ERKs
AKT
ovary
Online Access:https://www.mdpi.com/1422-0067/22/24/13520

Internet

https://www.mdpi.com/1422-0067/22/24/13520

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