Ras oncogene and Hypoxia-inducible factor-1 alpha (hif-1α) expression in the Amazon fish Colossoma macropomum (Cuvier, 1818) exposed to benzo[a]pyrene.

Ras oncogene and Hypoxia-inducible factor-1 alpha (hif-1α) expression in the Amazon fish Colossoma macropomum (Cuvier, 1818) exposed to benzo[a]pyrene.

Abstract Benzo[a]pyrene (B[a]P) is a petroleum derivative capable of inducing cancer in human and animals. In this work, under laboratory conditions, we analyzed the responses of Colossoma macropomum to B[a]P acute exposure through intraperitoneal injection of four different B[a]P concentrations (4,...

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Bibliographic Details
Main Authors: Grazyelle Sebrenski da Silva, Luciana Mara Lopes Fé, Maria de Nazaré Paula da Silva, Vera Maria Fonseca de Almeida e Val
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 2017-05-01
Series:Genetics and Molecular Biology
Subjects:
Ras oncogene
hif-1α
tambaqui
B[a]P
genotoxic damage
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572017000300491&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572017000300491&lng=en&tlng=en

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