Arterial Stiffening Moderates the Relationship Between Type-2 Diabetes Mellitus and White Matter Hyperintensity Burden in Older Adults With Mild Cognitive Impairment

Background: Cerebrovascular dysfunction has been proposed as a possible mechanism underlying cognitive impairment in the context of type 2 diabetes mellitus (DM). Although magnetic resonance imaging (MRI) evidence of cerebrovascular disease, such as white matter hyperintensities (WMH), is often obse...

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Bibliographic Details
Main Authors: Madeleine L. Werhane, Kelsey R. Thomas, Katherine J. Bangen, Alexandra J. Weigand, Emily C. Edmonds, Daniel A. Nation, Erin E. Sundermann, Mark W. Bondi, Lisa Delano-Wood
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2021.716638/full