Arterial Stiffening Moderates the Relationship Between Type-2 Diabetes Mellitus and White Matter Hyperintensity Burden in Older Adults With Mild Cognitive Impairment
Background: Cerebrovascular dysfunction has been proposed as a possible mechanism underlying cognitive impairment in the context of type 2 diabetes mellitus (DM). Although magnetic resonance imaging (MRI) evidence of cerebrovascular disease, such as white matter hyperintensities (WMH), is often obse...
Main Authors: | Madeleine L. Werhane, Kelsey R. Thomas, Katherine J. Bangen, Alexandra J. Weigand, Emily C. Edmonds, Daniel A. Nation, Erin E. Sundermann, Mark W. Bondi, Lisa Delano-Wood |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-10-01
|
Series: | Frontiers in Aging Neuroscience |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fnagi.2021.716638/full |
Similar Items
-
Pathological functional impairment: Neuropsychological correlates of the shared variance between everyday functioning and brain volumetrics
by: Robert P. Fellows, et al.
Published: (2022-12-01) -
Reduced Regional Cerebral Blood Flow Relates to Poorer Cognition in Older Adults With Type 2 Diabetes
by: Katherine J. Bangen, et al.
Published: (2018-09-01) -
Prediabetes Is Associated With Brain Hypometabolism and Cognitive Decline in a Sex-Dependent Manner: A Longitudinal Study of Nondemented Older Adults
by: Erin E. Sundermann, et al.
Published: (2021-02-01) -
Cerebral Blood Flow and Amyloid-β Interact to Affect Memory Performance in Cognitively Normal Older Adults
by: Katherine J. Bangen, et al.
Published: (2017-06-01) -
Pulse pressure and APOE ε4 dose interact to affect cerebral blood flow in older adults without dementia
by: Lauren Edwards, et al.
Published: (2024-01-01)