Artificial Intelligence Uncovers Natural MMP Inhibitor Crocin as a Potential Treatment of Thoracic Aortic Aneurysm and Dissection

Artificial Intelligence Uncovers Natural MMP Inhibitor Crocin as a Potential Treatment of Thoracic Aortic Aneurysm and Dissection

Thoracic aortic aneurysm and dissection (TAAD) is a lethal cardiovascular condition without effective pharmaceutical therapy. Identifying novel drugs that target the key pathogenetic components is an urgent need. Bioinformatics analysis of pathological studies indicated “extracellular matrix organiz...

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Bibliographic Details
Main Authors: Feiran Qi, Yan Liu, Kunlin Zhang, Yanzhenzi Zhang, Ke Xu, Mei Zhou, Huinan Zhao, Shuolin Zhu, Jianxin Chen, Ping Li, Jie Du
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
thoracic aortic aneurysm and dissection
drug therapy
matrix metallopeptidase
crocin
natural compound
artificial intelligence
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.871486/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2022.871486/full

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