Quantitative RNA assessment and long-term stability in the FFPE tumor samples using Digital Spatial Profiler

Background: Long-term storage of tissue slides has been reported to induce reduced biomarker (e.g. proteins and messenger RNA) detection. This study aimed to evaluate the impact of long-term storage time (0, 16, 24 and 36 weeks) and treatment conditions (non-paraffin and paraffin dipping) at 4°C on...

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Bibliographic Details
Main Authors: S. Gupta, T. Chen, B. Destenaves
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:Immuno-Oncology and Technology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S259001882100037X